Vitamin C is one of the most celebrated skincare ingredients—not just for anti-ageing but for overall skin health. It stands alongside powerhouse actives like Retinol, Niacinamide, and exfoliating acids, delivering impressive benefits in multiple ways. But what exactly does it do, and how should you use it for the best results?
At Face Dr, we know how powerful the right Vitamin C serum can be. In this guide, we’ll explore why it deserves a spot in your routine and introduce our top product picks that we believe will deliver the best results for you.
In This Article
- How Vitamin C Transforms Your Skin
- Pure Vitamin C vs. Its Derivatives – What’s the Difference?
- Best Practices for Vitamin C Serum
- Our Best Vitamin C Serum Picks
Book your free video skincare consultation
How Vitamin C Transforms Your Skin Inside?
Vitamin C, in its purest form (Ascorbic Acid), is a powerhouse ingredient that delivers multiple skin benefits. From fading pigmentation and supporting acne healing to reducing inflammation and boosting collagen, it plays a key role in maintaining healthy, youthful-looking skin. But how exactly does it work?
5 Key Benefits of Vitamin C

- Enhances Sun Protection – Works under SPF to improve its effectiveness
- Boosts Collagen Production – Helps maintain skin firmness and elasticity
- Fades Dark Spots – Targets hyperpigmentation for a more even skin tone
- Restores Radiance – Revives dull skin for a natural glow
- Powerful Antioxidant Protection – Shields the skin from environmental damage
Antioxidant Defence; Sun Protection Boost
Vitamin C is a water-soluble antioxidant that fights free radicals—unstable molecules that accelerate skin ageing. Since free radicals come from everyday exposure to pollution, UV rays, and even oxygen, antioxidant protection is essential. Using Vitamin C in your morning routine also enhances the effectiveness of your sunscreen, making it a must-have for any anti-ageing regimen.
Collagen Support for Firm, Smooth Skin
Wrinkles? Loss of elasticity? Vitamin C helps by stimulating your skin’s natural collagen production—something that topical collagen creams can’t do. Since collagen is the protein responsible for keeping skin firm and plump, boosting its levels can help maintain a youthful appearance over time.
Brightening & Pigmentation Reduction
Pigmentation concerns take patience, but Vitamin C can speed up results. It works by inhibiting Tyrosinase, the enzyme responsible for melanin production, which helps to prevent and fade dark spots. For even better results, pair it with exfoliating acids, Retinol, and Niacinamide—but always remember to wear SPF!

Instant Glow-Boosting Effect
Environmental stress and UV damage can leave skin looking dull and tired. Thanks to its antioxidant power, Vitamin C revitalises the complexion by supporting healthy cell function and restoring your skin’s natural radiance. The best part? This effect can be seen in just a few weeks!
Pure Vitamin C vs. Its Derivatives – What’s the Difference?
When a skincare ingredient is truly powerful, it often comes with multiple derivatives—and Vitamin C is no exception. While pure Ascorbic Acid offers the most potent benefits, its derivatives can be excellent alternatives. They may not deliver every single effect of pure Vitamin C, but many still provide impressive antioxidant protection, collagen support, and brightening effects.
But why would you need an alternative in the first place? Let’s take a look at why you might consider one of these derivatives
Pure Vitamin C (Ascorbic Acid, AA) – The Powerhouse Antioxidant
Most research focuses on pure Ascorbic Acid (also known as L-Ascorbic Acid) because it delivers the full spectrum of Vitamin C’s benefits—antioxidant protection, collagen boost, brightening effects, and even anti-inflammatory properties. Over time, it also improves skin density and balance.
For maximum impact, Ascorbic Acid works best in concentrations between 10-20%, with 15% being the sweet spot. To enhance its stability and performance, it's often combined with other ingredients like Vitamin E and Ferulic Acid. This legendary trio enhances sun protection and antioxidant power, making the formula up to eight times more effective than Vitamin C alone!
Why Do We Need Vitamin C Derivatives?

As amazing as pure Vitamin C is, it has some drawbacks— it's unstable, degrades quickly in water, and isn’t easily absorbed by the skin. High concentrations can also cause irritation, especially for sensitive skin.
This is where Vitamin C derivatives come in! These stable alternatives are gentler on the skin, better absorbed, and often provide most of the benefits of pure Vitamin C. They’re ideal for sensitive or rosacea-prone skin.
So, which derivatives are the most powerful? Let’s take a look!
- Ethyl Ascorbic Acid (EAC) is a stable and effective Vitamin C derivative. It dissolves in both water and oil, and in the skin, it converts into pure Vitamin C. It offers antioxidant and anti-inflammatory benefits, boosts collagen production, and is particularly effective for reducing pigmentation.
- Ascorbyl Glucoside is another stable option that’s easier to formulate and has similar benefits to pure Vitamin C, though in milder amounts. It helps with collagen production, pigmentation, and provides antioxidant protection. It's also ideal for sensitive skin at concentrations of 10-12%.
- Tetrahexyldecyl Ascorbate (THDA) is oil-soluble and more stable than pure Vitamin C. It’s known for its strong collagen-boosting and pigmentation-fighting effects, along with antioxidant and anti-inflammatory properties.
-
Sodium Ascorbyl Phosphate (SAP) stands out for its anti-inflammatory effects, especially for acne-prone skin. It also has antioxidant benefits and helps with pigmentation, but its main strength is its antibacterial properties, making it great for combating acne-causing bacteria.
Best Practices for Vitamin C Serum
Vitamin C is a powerhouse antioxidant with a brightening and sun protection-boosting effect, so it's ideal to use your Vitamin C serum in the morning. It's easiest to apply with lightweight, watery formulae or gels containing Vitamin C derivatives. If you have dry skin or don't mind a slower absorption, you might prefer oilier or creamier formulae, but generally, we recommend saving those for nighttime. You'll still get all the benefits without missing out on the sunscreen-boosting effect.
Tips for Using Vitamin C

- It's great for all skin types, but if you have sensitive skin, start slowly. Begin by adding it once a week and gradually increase the frequency to avoid irritation.
- Vitamin C is effective for treating dark spots and pigmentation, but remember to wear sunscreen daily to get the full effect.
- Be cautious when using Vitamin C alongside retinol or exfoliants in the same routine.
- While not all Vitamin C products need refrigeration, avoid exposing them to high heat and light, as this can reduce their effectiveness.
If you would like to start your skincare journey
Book your free video skincare consultation
Is Vitamin C Safe During Pregnancy?
Vitamin C is considered safe for use during pregnancy and breastfeeding, along with other gentle ingredients like niacinamide, zinc, hyaluronic acid, and peptides. However, when opting for a brightening Vitamin C serum, be cautious about the ingredient list, as some formulae may also contain Arbutin. Since arbutin is a derivative of hydroquinone, it's recommended that it is avoided during pregnancy. Always check the ingredients and consult your doctor if you're unsure.
Our Best Vitamin C Serum Picks
We’ve handpicked the top Vitamin C serums to help you achieve brighter, more radiant skin. Whether you’re looking for a gentle formula or something more potent, these products cater to all needs and preferences.
1. Glytone Age Defying C+ Advanced Antioxidant Serum

This advanced serum contains Tetrahexyldecyl Ascorbate, a stable, lipid-soluble Vitamin C, to brighten the skin and protect against oxidative stress. It reduces the appearance of fine lines and wrinkles, supports the moisture barrier, and offers antioxidant protection. With Vitamin E, Ergothioneine, Pomegranate Seed Extract, and Kakadu Plum, it nourishes, hydrates, and helps fight premature ageing. Arbutin further brightens the skin, evens tone and boosts radiance.
Best for: Premature ageing, post-procedure care, and skin in need of antioxidant protection.
Available for £82.00 at Face Dr.
2. Obagi Professional-C® Serum 20%

This potent serum features L-Ascorbic Acid, the most effective and active form of Vitamin C, to provide maximum antioxidant protection. It helps to brighten the skin, reduce pigmentation, and promote collagen production, improving the appearance of fine lines and wrinkles. The addition of Ascorbyl Glucoside offers further antioxidant benefits, ensuring your skin is protected against environmental stressors. With consistent use, this serum helps to strengthen the skin barrier and renew the skin, leaving it glowing and radiant.
Best for: Dull skin, fine lines, wrinkles, and pigmentation.
Available for £170.00 at Face Dr.
3. ZO Skin Health ZO Vitamin C Self-Activating 10%

This advanced serum features a potent blend of Ascorbic Acid and Tetrahexyldecyl Ascorbate, two powerful forms of Vitamin C, designed to deeply brighten the skin and reduce the appearance of fine lines and wrinkles. The oil-soluble Tetrahexyldecyl Ascorbate allows for deeper penetration, while the Ascorbic Acid works to exfoliate and even skin tone. Adding Tocopheryl Acetate and Coenzyme Q10 enhances antioxidant protection, protecting the skin from free radical damage and promoting repair.
Best for: Dull skin, fine lines, wrinkles, and uneven skin tone.
Available at Face Dr.
4. Clinical Skin Vitamin C Pro-Collagen Serum

Packed with Ascorbic Acid and Tetrahexyldecyl Ascorbate, this serum brightens and evens skin tone while boosting collagen production. Ergothioneine and Glutathione provide antioxidant protection, while Ceramides and Glycerin deeply hydrate and restore moisture. Soothing Chamomile and Lavender Extracts calm the skin, making it ideal for dry, dull, and uneven skin. Clinically proven to leave skin firmer, smoother, and glowing.
Best for: Dry skin, uneven tone, fine lines, and collagen support.
Available for £110.00 at Face Dr.
5. Paula's Choice C15 Super Booster
With 15% pure Vitamin C, this serum works to brighten, even skin tone, and reduce pigmentation. Combined with powerful antioxidants like Vitamin E, Ferulic Acid, and Ergothioneine, it helps protect against environmental stressors. The addition of peptides boosts collagen production, smoothing fine lines and improving skin texture for a more youthful appearance. It's lightweight, fast-absorbing formula leaves the skin glowing and refreshed.
Best for: Dull skin, uneven tone, fine lines, and those looking to improve skin texture and radiance.
Available for £52.00 at https://www.paulaschoice.co.uk/.
6. Skintegra Superba C
This smart ageing serum contains 10% Sodium Ascorbyl Phosphate (SAP), a Vitamin C derivative that helps even out skin tone and provides antioxidant protection. It also works effectively against acne and pigmentation. Enhanced with Vitamin E and Ferulic Acid, it boosts skin radiance and strengthens the effectiveness of sunscreen when used in the morning. SAP is known for its gentle, yet powerful action against Cutibacterium acnes, making it ideal for acne-prone and sensitive skin, especially those with rosacea.
Best for: Acne-prone skin, sensitive skin, rosacea, pigmentation, and those seeking antioxidant protection and a more even skin tone.
Available for £24.32 at https://www.beautytheshop.com/uk.
7. JUMISO All Day Vitamin Brightening & Balancing Facial Serum
This serum combines pure Ascorbic Acid with synergistic Niacinamide to brighten and even out your skin tone while enhancing antioxidant protection. The combination of these two powerhouse ingredients helps reduce dark spots and improve skin texture. Soothing Centella Asiatica and Panthenol work to calm and hydrate sensitive skin. With a lower concentration of Vitamin C, it’s an ideal choice for beginners looking to experience the benefits of this powerful ingredient without irritation. A must-try for fans of Korean skincare, known for its gentle yet effective formulae.
Best for: Those new to Vitamin C who want a gentle introduction to its benefits.
Available for £22.80 at https://pureseoul.co.uk/.
In Conclusion
Vitamin C is a powerful ingredient that brightens, boosts collagen production, and fights signs of ageing. With our expert recommendations and Face Dr.’s trusted guidance, we've handpicked the best Vitamin C serums to suit your needs. Take the next step toward glowing, youthful skin—incorporate Vitamin C into your routine today and experience the difference!
If you're unsure about incorporating Vitamin C into your skincare routine or have specific concerns, Face Dr is here to help. Our team of skincare professionals is always available to provide personalised advice and guide you in the right direction on your skincare journey. Don’t hesitate to reach out for expert recommendations and tailored solutions.
Book your free video skincare consultation
Here are some articles that might interest you:
- Learn more about Glytone Age Defying PHA+ Renewing Eye Cream
- What is Vitamin C in skincare and how does it work?
- 6 skincare ingredients that you should and shouldn't mix