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Was £160 Now £128 Was £160, now £12850ml | 1.7 Fl. Oz.

Key Benefits

  • Reduces damage-induced pigmentation, and wrinkles.
  • Visibly reduces stubborn discoloration by -23%.
  • Minimises laser downtime and complements the outcome*.
  • *after 1 hr. vs. untreated skin.
Targets
  • Ageing skin Ageing skin
  • Sensitive skin Sensitive skin
When to use
  • Morning Morning
  • Evening Evening
Product details

SkinCeuticals' Advanced RGN-6 is a comforting, non-greasy skin rejuvenation cream designed to support skin barrier recovery and repair. Using biomimetic technology, it acts like a “second skin,” helping to restore and strengthen the skin while reducing the appearance of discolouration, fine lines, and wrinkles.

Tested with both ablative and non-ablative laser treatments, Advanced RGN-6 can complement aesthetic procedures, minimising downtime and post-treatment irritation, while also being safe for daily use. Its patented formula combines six key ingredients to activate the skin’s natural repair process and promote a visibly rejuvenated, healthy-looking complexion.

Fragrance- and alcohol-free, it is gentle enough for sensitive skin, supporting barrier recovery and overall skin resilience.

For use on fully healed skin only. Always consult a medical professional before applying after aesthetic treatments.

Directions for use
  • Once or twice daily after cleansing, apply 1-2 pumps of Advanced RGN-6 to the palm of the hand and press into the skin of the forehead cheeks and chin.
  • Blend the product into the skin. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen.
Key ingredients
  • 10% Glyco-Repair™ - A nutrient-dense derivative of carob seeds, glyco-repair™ helps to trigger barrier repair and renew skin texture.
  • 1 Eperuline - Derived from eperua falcata bark, eperuline has been shown to soothe skin, reduce signs of aging, and combat laser-induced oxidative stress.
  • 2 Niacinamide - Also known as vitamin B3, this water-soluble vitamin is found naturally in yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. It has been shown to help reduce the appearance of skin discoloration.
  • 3% Acetyl Tetrapeptide-9 - A powerful signal peptide, acetyl tetra-peptide 9 helps support skin's structure and integrity for firmer, more resilient skin.
  • 0.2% Ectoin - An amino acid derivative and extremolyte (molecule that helps stabilize and protect organisms under extreme conditions), ectoin helps prevent oxidative damage and discoloration.
  • 0.2% Bioceramide 603 - A patented, exclusive ceramide analog, bioceramide-603 is shown to target discoloration and post-treatment redness.
All ingredients
Aqua / Water / Eau, Glycerin, Ethyl Oleate, Niacinamide, Squalane, C12-16 Alcohols, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter / Shea Butter, Maltodextrin, Ammonium Polyacryloyldimethyl Taurate, Phenoxyethanol, Dimethicone, Palmitic Acid, Hydrogenated Lecithin, Cetyl Alcohol, Ceratonia Siliqua Seed Extract / Carob Seed Extract, Caprylyl Glycol, 2-Oleamido-1,3-Octadecanediol, Ectoin, Tocopherol, Eperua Falcata Bark Extract, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Adenosine, Sodium Hydroxide, Sodium Benzoate, Acetyl Tetrapeptide-9, Citric Acid

Dr Julia Langford

Clinical Director & Aesthetics Doctor

Experts explain 

Skin barrier recovery powerhouse

Supporting the skin barrier is essential for both daily skin health and post-treatment recovery. SkinCeuticals Advanced RGN-6 uses biomimetic technology to act like a second skin, helping to accelerate barrier repair, soothe irritation, and reduce the appearance of fine lines and discoloration. It’s ideal for clients who want rejuvenated, resilient skin at home or following aesthetic treatments.

Advanced RGN-6
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Advanced RGN-6 FAQs

What is SkinCeuticals Advanced RGN-6?

SkinCeuticals Advanced RGN-6 is a non-greasy skin rejuvenation cream that supports barrier repair, hydration, and overall skin resilience. Its patented formula combines six key ingredients to help restore skin, reduce the appearance of fine lines, wrinkles, and discolouration, and provide a comforting “second skin” effect.

Who should use Advanced RGN-6?

This cream is suitable for clients with sensitive, ageing, or compromised skin, as well as those recovering from laser or other aesthetic treatments. It is ideal for anyone looking to support skin repair, maintain barrier health, and improve the visible signs of ageing.

How do I use SkinCeuticals Advanced RGN-6?

Apply a thin layer to clean, fully healed skin once or twice daily, as needed. It can be used post-treatment to complement aesthetic procedures or as part of a daily skincare routine to maintain skin health and resilience.

Can I use Advanced RGN-6 with other skincare products?

Yes. It can be layered with other serums, moisturisers, and sunscreens. Avoid applying on broken or untreated skin; always ensure the skin is fully healed after procedures before use.

Is Advanced RGN-6 suitable for sensitive skin?

Yes. Fragrance- and alcohol-free, its gentle, soothing formula is ideal for sensitive and reactive skin, providing comfort, hydration, and barrier support.

How long does it take to see results?

Many clients notice improved comfort, hydration, and skin resilience within hours, with ongoing improvement in texture, tone, and visible signs of ageing over several weeks of consistent use.

Can I use this cream after aesthetic treatments?

Yes. Advanced RGN-6 has been tested with ablative and non-ablative laser procedures. It helps reduce post-treatment irritation and downtime, but should only be applied to fully healed skin. Always consult a medical professional before use after aesthetic procedures.
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