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SkinCeuticals

A.G.E Interrupter Advanced

£175 48ml | 1.6 Fl. Oz.

Flexible payment options including

Key Benefits

  • Targets visible ageing.
  • Helps reverse visible signs of ageing impacted by collagen decline and glycation, including wrinkling, laxity, and dullness.
  • Restores the skin's firmness.
Targets
  • Ageing skin Ageing skin
  • Dry skin Dry skin
When to use
  • Morning Morning
  • Evening Evening
Product details

SkinCeuticals' A.G.E. Interrupter Advanced is a powerful anti-ageing treatment cream specifically formulated to combat advanced signs of ageing caused by the accumulation of advanced glycation end products (A.G.E.s). This serum helps restore skin firmness, reduce deep wrinkles, and improve elasticity while promoting a more youthful, radiant complexion. Its advanced formulation is ideal for clients with mature or ageing skin seeking to target stubborn structural ageing and enhance skin resilience.

Directions for use
  • Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest.
  • If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.
Key ingredients
  • 18% Concentrated Proxylane - Helps support skin’s integrity and correct visible signs of Ageing, like wrinkles and laxity.
  • 4.25% Wild Fruit Flavonoids - Combination of blueberry and pomegranate extracts help reduce oxidative stresCB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.
  • 0.1% Glycyrrhetinic Acid - Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.
  • 3% Hepes - Activates natural enzymes in skin to promote even cell turnover while hydrating skin.
  • 1% Niacinamide - Water-soluble vitamin, also known as vitamin B3, soothes and helps support skin’s moisture barrier.
All ingredients
Aqua / Water, Glycerin, Propylene Glycol, Butylene Glycol. Potassium Phosphate, Polysorbate 80, Phenoxyethanol, Sodium Chloride, Hexylene Glycol, Dipotassium Phosphate, Polyglyceryl-4 Caprate, Sodium Hyaluronate, Peumus Boldus Leaf Extract, Disodium Edta, Olea Europaea Leaf Extract/olive Leaf Extract, Myrtrimonium Bromide, Benzophenone-4, Rosmarinus Officinalis Leaf Extract/rosemary Leaf Extract, Parfum/fragrance, Xanthan Gum, Citrus Grandis Fruit Extract/grapefruit Fruit Extract, Sodium Benzoate, Cucumis Sativus Fruit Extract/cucumber Fruit Extract, Thymus Vulgaris Flower/leaf Extract - Thyme Flower/leaf Extract, Lactic Acid, Benzyl Benzoate, Potassium Sorbate, Benzyl Alcohol, Alpha-isomethyl Ionone, Morus Alba Root Extract, Linalool, Ci 42090/blue 1, Ci 19140/yellow 5, (code F.i.l. d249771/1) *Please be aware that ingredient lists for products in our brand are updated regularly. Please refer to the ingredient list on the product package for the most up-to-date list of ingredients to ensure it is suitable for your personal use.

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Dr Julia Langford

Clinical Director & Aesthetics Doctor

Experts explain 

Ageing isn’t just about fine lines

Ageing isn’t just about fine lines—it’s also about structural changes in the skin caused by glycation. SkinCeuticals A.G.E. Interrupter Advanced helps reduce deep wrinkles, restore firmness, and improve elasticity, targeting stubborn signs of ageing for a smoother, more youthful-looking complexion.

A.G.E Interrupter Advanced
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Reviews

A.G.E Interrupter Advanced FAQs

What is SkinCeuticals A.G.E. Interrupter Advanced?

It is an anti-ageing serum that targets deep wrinkles, firmness loss, and skin structural ageing caused by A.G.E.s, helping restore elasticity and a youthful appearance.

Who should use A.G.E. Interrupter Advanced?

Ideal for clients with mature or ageing skin, or anyone concerned with deep wrinkles, sagging, or structural signs of ageing. Suitable for most skin types.

How do I use SkinCeuticals A.G.E. Interrupter Advanced?

Apply 2–3 drops to clean, dry skin morning and evening. Smooth over the face, neck, and décolletage before moisturisers or sunscreen.

Can it be used with other skincare products?

Yes. It can be safely layered with serums, moisturisers, and SPF, as well as other corrective treatments, for a comprehensive anti-ageing routine.

Is this serum suitable for sensitive skin?

Yes. The formulation is gentle and well-tolerated, including on mature or reactive skin. Patch testing is recommended for very sensitive skin.

How long does it take to see results?

Clients often notice improved firmness and smoother skin texture within 4–6 weeks, with continued reduction in deep wrinkles and improved elasticity over time with regular use.

Does it target structural ageing?

Yes. Its advanced formulation reduces advanced glycation end products (A.G.E.s), which are a key contributor to loss of skin firmness and deep wrinkles.

Can it be used daily?

Absolutely. Designed for daily use, morning and evening, to maintain skin firmness, elasticity, and resilience.
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