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£79 30ml | 1 Fl. Oz.

Key Benefits

  • Visibly reduces fine lines and wrinkles.
  • Boosts skin elasticity and firmness.
  • Deeply hydrates and plumps the skin.
  • Improves skin radiance and luminosity.
  • Supports skin's natural repair and regeneration.
  • Suitable for all skin types, including sensitive skin.
Targets
  • Ageing skin Ageing skin
  • Dry skin Dry skin
  • Sensitive skin Sensitive skin
When to use
  • Morning Morning
  • Evening Evening
Product details

Medik8 Exo-PDRN Prismatic

Meet the future of skin regeneration. Exo-PDRN Prismatic+ is Medik8's most advanced bio-regenerative serum, combining the power of PDRN (Polydeoxyribonucleotide) technology with a prismatic blend of skin-renewing actives to visibly restore, plump, and illuminate skin from within.

Inspired by the science of cellular repair, this luxurious serum works at a deep level to stimulate the skin's natural regeneration process — reducing the appearance of fine lines, improving elasticity, and delivering a luminous, glass-skin finish with every use.

Directions for use
  • Apply 2–3 drops to cleansed skin morning and/or evening.
  • Gently press into the face, neck, and décolletage.
  • Follow with your preferred moisturiser and SPF (AM).
  • For best results, use consistently as part of your daily skincare routine.
Key ingredients
  • PDRN (Polydeoxyribonucleotide) - Stimulates cellular regeneration and tissue repair for visibly younger-looking skin.
  • Exosome Technology - Delivers active ingredients deep into the skin for enhanced efficacy.
  • Hyaluronic Acid - Provides intense, multi-level hydration.
  • Niacinamide - Brightens skin tone and minimises the appearance of pores.
  • Peptide Complex - Supports collagen synthesis and skin firmness.
All ingredients
Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate

Reviews

Exo-PDRN Prismatic+ FAQs

What is Medik8 Exo-PDRN Prismatic+?

Medik8 Exo-PDRN Prismatic+ is an advanced rejuvenating serum designed to support skin recovery, improve luminosity, enhance skin texture and strengthen the skin barrier. The formula combines vegan Prismatic PDRN, a Triple Exosome Complex, GF MiniProtein™ and an ATP Precursor to help support the skin's natural rejuvenation processes.

What does PDRN stand for in skincare?

PDRN stands for Polydeoxyribonucleotide. It is a regenerative ingredient that has become popular for supporting skin repair, hydration and collagen production. Medik8 uses a vegan version called Prismatic PDRN rather than animal-derived PDRN.

What is unique about Medik8 Prismatic PDRN?

Medik8's Prismatic PDRN features a tetrahedral structure designed to improve skin absorption compared to traditional topical PDRN ingredients. The brand states it offers 100% better absorption and deeper penetration than conventional PDRN technologies.

What are exosomes in skincare?

Exosomes are microscopic messenger particles that support communication between skin cells. In skincare, they are used to help support skin renewal, resilience and recovery. Medik8 Exo-PDRN Prismatic+ contains a Triple Exosome Complex designed to enhance the skin's natural signalling processes.

What are the benefits of Medik8 Exo-PDRN Prismatic+?

Key benefits include: Improved skin radiance and luminosity Smoother-looking skin texture Enhanced skin barrier function Reduced appearance of fine lines and wrinkles Improved skin firmness Support for post-treatment skin recovery Calmer-looking skin with reduced visible redness According to Medik8, visible improvements in skin vitality and barrier function were observed within seven days in clinical testing.

Is Medik8 Exo-PDRN Prismatic+ suitable for sensitive skin?

Yes. Medik8 has formulated Exo-PDRN Prismatic+ for all skin types, including sensitive skin. The formula focuses on supporting skin recovery and barrier health, making it suitable for skin experiencing dryness, redness or sensitivity. As with any skincare product, a patch test is recommended before first use.

Can I use Medik8 Exo-PDRN Prismatic+ after aesthetic treatments?

Yes. Medik8 specifically positions the serum as a supportive product for skin recovery and resilience. It may be a useful addition following treatments such as microneedling, chemical peels, laser procedures or injectable skin rejuvenation treatments, subject to your clinician's advice.

How do you use Medik8 Exo-PDRN Prismatic+?

After cleansing, apply 1–2 pumps evenly across the face and neck morning and evening. Allow the serum to absorb fully before applying moisturiser and SPF during the daytime.

Can I use Medik8 Exo-PDRN Prismatic+ with retinol?

Yes. Medik8 Exo-PDRN Prismatic+ can be incorporated into a retinol or retinal routine. Many users apply the serum before their retinoid products to help support hydration, skin comfort and barrier function.

Can I use Medik8 Exo-PDRN Prismatic+ with vitamin C?

Yes. The serum can be used alongside vitamin C. Apply Exo-PDRN Prismatic+ after cleansing and follow with your preferred antioxidant serum, moisturiser and SPF in the morning.

How long does it take to see results from Medik8 Exo-PDRN Prismatic+?

Clinical testing reported improvements in skin barrier function, luminosity, volume and tone within seven days. Improvements in wrinkle appearance and firmness were observed within 14 days, with continued benefits over longer-term use.

Is topical PDRN effective?

Research into topical PDRN continues to evolve. While injectable PDRN currently has the strongest evidence base, skincare brands such as Medik8 have developed technologies aimed at improving topical delivery and skin absorption. Medik8's Prismatic PDRN technology was specifically designed to address traditional absorption challenges associated with PDRN.

Is Medik8 Exo-PDRN Prismatic+ worth it?

For those looking for a premium skin rejuvenation serum focused on barrier support, recovery, luminosity and healthy ageing, Medik8 Exo-PDRN Prismatic+ offers one of the most advanced topical combinations of PDRN, exosomes and growth-factor-inspired technology currently available. Individual results will vary depending on skin type and concerns.
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