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Was Now £0 Was , now £048ml | 1.6 Fl. Oz.

Key Benefits

  • Visibly reduces deep set wrinkles + pores that neurotoxins alone do not treat*.
  • Up to -33% visible wrinkles, -30% pore size​.
  • Boosts hydration by up to +94% in just 1 hour.
  • Physician tested to complement neurotoxin injections.
  • Suitable for all skin types and tones, even sensitive skin.
  • Smooths skin texture with patent-pending Myrixin™ and advanced peptides.
  • Achieves glass skin appearance when paired with P-TIOX serum.
Targets
  • Ageing skin Ageing skin
When to use
  • Morning Morning
  • Evening Evening
Product details

Meet your new secret weapon against expression lines. SkinCeuticals P-TIOX Anti-Wrinkle Cream is a targeted treatment that works where it matters most — on the contraction lines caused by repeated facial movements. Powered by an advanced peptide complex, this rich yet fast-absorbing cream visibly smooths and softens lines around the eyes, forehead, and mouth, leaving skin looking refreshed and more youthful with every use.

  • Advanced Peptide Complex — hexapeptide and dipeptide technology targets contraction lines at the source
  • Clinically proven to reduce the appearance of expression lines
  • Niacinamide brightens and evens skin tone
  • Hydrating formula smooths texture and boosts radiance
  • Lightweight, fast-absorbing cream texture suitable for daily use
Directions for use
  • Twice daily, after applying a corrective serum, dispense a small amount into clean hands.
  • Gently press cream evenly into skin on face, neck and around the eyes.
  • Follow with a SkinCeuticals sunscreen.
Key ingredients
  • 10% Mytrixin -A potent skin-firming complex that targets the visible signs of ageing by strengthening the skin's structural support for a visibly lifted, more resilient complexion.
  • 2% Tripeptide - A signalling peptide that communicates with skin cells to stimulate collagen production, helping to smooth fine lines and restore a plumper, more youthful appearance.
  • 1% Crystalide Micropeptide - A biomimetic micropeptide that accelerates skin renewal and enhances radiance by encouraging cell turnover for a fresher, more luminous complexion.
  • 5% Niacinamide + LHA + Zinc PCA - A triple-action blend that regulates sebum, gently exfoliates congested pores, and visibly reduces redness for clearer, more balanced skin.
All ingredients
Aqua/Water/Eau, Butylene Glycol, Niacinamide, Glycerin, Dicaprylyl Carbonate, Pentylene Glycol, Cetearyl Alcohol, 1,2-Hexanediol, Isododecane, C14-22 Alcohols, Caprylic/Capric Triglyceride, Vinyl Dimethicone, Macadamia Integrifolia Seed Oil, Glyceryl Stearate SE, C12-20 Alkyl Glucoside, Nymphaea Alba Flower Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butyrospermum Parkii Butter/Shea Butter, C12-16 Alcohols, Tromethamine, Psidium Guajava Fruit Extract, Camellia Sinensis Leaf Extract, Allium Sativum Bulb Extract/Garlic Bulb Extract, Zinc PCA, Capryloyl Salicylic Acid, Psidium Guajava Leaf Extract, Luffa Cylindrica Fruit Extract, Hydrogenated Lecithin, Palmitic Acid, Cetyl Palmitate, Ethylhexylglycerin, Adenosine, Sorbitan Stearate, Polysorbate 80, Tocopherol, Ceramide NP, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Benzoate, Citric Acid, Palmitoyl Tetrapeptide-10

Reviews

P-TIOX Anti-Wrinkle Cream FAQs

What is SkinCeuticals P-TIOX Anti-Wrinkle Cream?

SkinCeuticals P-TIOX Anti-Wrinkle Cream is a high-potency, peptide-powered moisturiser formulated to visibly reduce deep-set wrinkles and minimise the appearance of pores. Powered by a patent-pending formula containing 10% Mytrixin, 2% Tripeptide, 1% Crystalide Micropeptide, and 5% Niacinamide with LHA and Zinc PCA, it targets visible signs of ageing including textural roughness, pore visibility, and deep contraction lines. Its micro-melting cream texture delivers intense hydration without a greasy finish, leaving skin visibly smoother and more radiant.

What does P-TIOX Anti-Wrinkle Cream do for the skin?

P-TIOX Anti-Wrinkle Cream works to visibly reduce deep-set wrinkles and pores that neurotoxin injections alone do not address. Clinical data shows up to a 33% reduction in visible wrinkles and a 30% reduction in pore appearance with consistent use. It also improves skin texture, enhances radiance, and provides 24-hour hydration while strengthening the skin's barrier. When used alongside the P-TIOX Serum, results are further enhanced, with visible improvements in glass skin clarity and surface smoothness reported in as little as one week.

Who is P-TIOX Anti-Wrinkle Cream suitable for?

P-TIOX Anti-Wrinkle Cream is suitable for men and women of all skin tones who are looking to address visible signs of ageing, including deep-set wrinkles, enlarged pores, and uneven skin texture. It is fragrance-free, making it well tolerated by sensitive skin. It is also clinically tested and suitable for use between neurotoxin injections, making it particularly relevant for those who supplement their injectable treatments with medical-grade skincare at home.

How do I use P-TIOX Anti-Wrinkle Cream?

Apply P-TIOX Anti-Wrinkle Cream to clean, dry skin in the morning and/or evening. Smooth a small amount evenly over the face and neck, avoiding the eye area unless your Skin Expert has advised otherwise. Follow with SPF in the morning. For best results, use alongside the P-TIOX Serum — apply the serum first, allow it to absorb, then follow with the cream.

Can I use P-TIOX Anti-Wrinkle Cream with the P-TIOX Serum?

Yes — P-TIOX Anti-Wrinkle Cream is specifically designed to complement the P-TIOX Serum. When used together, the combination visibly enhances overall skin clarity and surface smoothness, with clinical results showing glass skin radiance achievable in as little as one week. Apply the serum first to clean skin, allow it to absorb fully, then apply the cream on top to lock in the active ingredients and provide lasting hydration.

Can P-TIOX Anti-Wrinkle Cream be used alongside neurotoxin injections?

Yes. P-TIOX Anti-Wrinkle Cream has been clinically tested for use alongside neurotoxin injections such as Botox. It is formulated to address the types of wrinkles and textural concerns that neurotoxin injections alone do not treat — particularly deep-set static lines and visible pores — making it an effective complement to injectable treatments as part of a comprehensive anti-ageing routine.

How long does it take to see results from P-TIOX Anti-Wrinkle Cream?

When used in combination with the P-TIOX Serum, visible improvements in skin clarity and surface smoothness have been reported in as little as one week. In terms of measurable clinical outcomes, up to a 33% reduction in visible wrinkles and a 30% reduction in pore appearance have been demonstrated with consistent use. For best results, the cream should be incorporated as a daily step in your morning and evening skincare routine.

Is P-TIOX Anti-Wrinkle Cream suitable for sensitive skin?

P-TIOX Anti-Wrinkle Cream is fragrance-free and has been tested across all skin tones. While it is generally well tolerated, including by those with sensitive skin, we recommend booking a free online skincare consultation with one of our Skin Experts at Face Dr before introducing any new medical-grade product into your routine. Our experts can advise on suitability for your specific skin type and concerns.

How does P-TIOX Anti-Wrinkle Cream differ from the P-TIOX Serum?

The P-TIOX Serum is a lightweight, fast-absorbing treatment that targets nine types of contraction lines using an advanced hexapeptide and dipeptide complex, and is primarily focused on expression wrinkles and glass skin radiance. The P-TIOX Anti-Wrinkle Cream builds on this with a richer, moisturising formula containing 10% Mytrixin, Tripeptide, and Crystalide Micropeptide to address deeper-set wrinkles, enlarged pores, and skin texture. Used together, they provide a more comprehensive anti-wrinkle treatment than either product achieves alone.

Where can I buy SkinCeuticals P-TIOX Anti-Wrinkle Cream in the UK?

SkinCeuticals P-TIOX Anti-Wrinkle Cream is available to purchase from Face Dr, an authorised UK stockist of SkinCeuticals. You can shop the full SkinCeuticals range at myfacedr.com. If you are unsure whether P-TIOX Cream is right for your skin, you can book a free online skincare consultation with one of our Skin Experts, who will assess your concerns and recommend the most appropriate products for your routine.
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