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Find out More About ZO Skin Health’s Peptide Facial Refining Concentrate

Medically Reviewed by Dr Julia Langford, MBBS MRCGP
Written by Annaliza Botsio
Published on

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Innovation in medical-grade skincare is always exciting, and September 2025 brought one of ZO Skin Health’s most anticipated launches: the Peptide Facial Refining Concentrate. Designed for clients who want to stay ahead in their anti-ageing routines, it represents the latest in professional, science-backed skincare.

At Face Dr, we combine medical expertise with years of experience in aesthetics to guide clients toward products that truly deliver. By focusing on clinically proven, medical-grade brands like ZO Skin Health, we ensure our clients have access to the most effective solutions for long-term skin health.

In this article, we’ll explore what makes the Peptide Facial Refining Concentrate so special, how it fits into an anti-ageing routine, and why it’s becoming a go-to for those seeking smoother, more youthful-looking skin.

  • What Are ZO Skin Health Products?
  • What Is ZO Skin Health Peptide Facial Refining Concentrate?
  • What Will It Do for My Skin?
  • How Does It Work in an Anti-Ageing Routine?
  • Key Ingredients in ZO Skin Health Peptide Facial Refining Concentrate
  • Who Would Benefit Most From Using It?
  • How to Incorporate It Into Your Skincare Routine
  • How Long Will a Bottle Last?
  • How Much Does ZO Skin Health Peptide Facial Refining Concentrate Cost?
  • How Can I Buy ZO Skin Health Peptide Facial Refining Concentrate?
  • Not Sure If This Product Is Right for You?
  • Summary: Should You Try ZO Skin Health Peptide Facial Refining Concentrate?

 

What Are ZO Skin Health Products?

ZO Skin Health Products

ZO Skin Health is a globally recognised medical-grade skincare brand founded by dermatologist Dr Zein Obagi, built on the principle that lasting skin health comes from science-led solutions. Each product combines advanced technologies, potent active ingredients, and precision delivery systems to target concerns such as pigmentation, sun damage, fine lines, and early signs of ageing, while remaining gentle on the skin. What sets ZO Skin Health apart is its focus on innovation and high-performance formulations, designed to deliver real, lasting results while strengthening the skin’s natural barrier to repair, protect, and function at its best.

As an authorised stockist, we at Face Dr provide expert guidance to help you select the right ZO Skin Health products for your individual needs, ensuring every routine is effective, personalised, and designed for lasting results.

 

What Is ZO Skin Health Peptide Facial Refining Concentrate?

Skin Health Peptide Facial Refining Concentrate

The ZO Skin Health Peptide Facial Refining Concentrate, launched in autumn 2025, introduces a new era of sculpting and anti-ageing skincare. This advanced serum is powered by four cutting-edge peptide technologies, working together to visibly smooth fine lines, improve elasticity, restore facial volume, and refine overall skin texture.

Ideal as a standalone daily treatment or as a complement to injectable procedures, it helps enhance facial geometry for a more lifted, sculpted appearance. Designed with both potency and gentleness in mind, this professional-grade formula delivers clinically shown results, supporting healthier, youthful-looking skin and adding radiance to your anti-ageing routine.

 

What Will It Do for My Skin?


The ZO Skin Health Peptide Facial Refining Concentrate is designed to transform your skin with a targeted, science-backed approach. Its advanced peptide formula supports cellular communication and dermal remodelling, helping smooth visible expression lines and static wrinkles while restoring lost volume for a fuller, more refined appearance.

In an independent 12-week clinical study of 49 participants aged 47–72:

  • 92% experienced a reduction in fine lines
  • 82% noticed fewer forehead wrinkles
  • 96% reported smoother skin
  • 84% observed visibly improved facial contours
  • 86% experienced enhanced fullness in facial hollow areas

These results translate into noticeable improvements for your skin:

  • Smoother, more lifted appearance: Peptides help soften both dynamic and static wrinkles for a natural, youthful look.
  • Enhanced facial structure and contours: By stimulating collagen and elastin production, the skin’s firmness, volume, and sculpted facial geometry are improved.
  • Hydration and plumpness: Promotes hyaluronic acid and lipid synthesis, leaving skin supple, radiant, and revitalised.

 If you’d like to learn more about how peptides work and why they’re such a powerful part of anti-ageing skincare, explore our Face Dr guide: What You Need to Know About Peptides.

 

How Does It Work in an Anti-Ageing Routine?

Woman in Robe Doing Skincare in Bathroom

The ZO Skin Health Peptide Facial Refining Concentrate fits effortlessly into professional skincare routines. Thanks to their gentle, non-irritating nature, peptides can be safely combined with other potent anti-ageing ingredients, like retinoids or vitamin C, allowing multiple strategies to complement each other for a more comprehensive approach. It also pairs effectively with in-clinic treatments like injectables, helping to maintain and extend their results while still delivering visible improvements when used on its own.

 

Key Ingredients in ZO Skin Health Peptide Facial Refining Concentrate


The Peptide Facial Refining Concentrate combines a targeted mix of peptides and innovative complexes to support a more youthful, sculpted appearance:

  • Acetyl Octapeptide-3: Reduces the appearance of expression lines by gently influencing muscle movement.
  • Acetyl Hexapeptide-8: Strengthens the deeper layers of the skin to improve firmness and address static wrinkles.
  • Refining Peptide Complex: Helps reshape facial contours and encourages structural support for a lifted look.
  • Volumising Tripeptide :Restores fullness to hollowed areas, creating a plumper, more defined facial profile.
  • Z-POLY™ Complex :A plant-based blend that hydrates, calms, and reinforces the skin barrier, aiding recovery and protecting against premature ageing.

This carefully balanced formula allows these powerful ingredients to work together, delivering visible improvements in texture, lift, and radiance, whether used alone or alongside professional treatments.

 

Who Would Benefit Most From Using It?

Model holding the ZO Skin Health Peptide Facial Refining Concentrate

The ZO Skin Health Peptide Facial Refining Concentrate is ideal for anyone looking to support a smoother, lifted, and more youthful-looking complexion. Its gentle, peptide-rich formula makes it suitable for a wide range of needs, including:

  • Clients having injectable treatments like muscle relaxant injections, dermal fillers, or skin boosters, to help maintain and enhance results.

  • Those seeking non-invasive alternatives to improve facial volume, lift, and skin texture.

  • Individuals noticing changes in facial volume or skin laxity, including those affected by weight loss or ageing.

  • Clients following ZO Skin Health protocols can layer it easily with other professional-grade products.

  • Anyone preparing for or recovering from procedures, helping the skin stay calm, hydrated, and resilient.

Formulated without alcohol or fragrance, it is gentle and suitable for all skin types.

If you’re unsure how it might fit into your routine or want personalised guidance, you can book a free online consultation with one of our Skin Experts at Face Dr, who will assess your skin and recommend the best approach for your individual needs.

 

How to Incorporate It Into Your Skincare Routine


Using the ZO Skin Health Peptide Facial Refining Concentrate is simple, but following the right sequence can help you get the most out of its potent ingredients. For best results, apply it twice daily, morning and evening, to clean, dry skin on the face and neck.

A recommended layering sequence within a ZO Skin Health routine is:

  • Step 1: Start with Daily Power Defense (DPD) to prepare and protect the skin.
  • Step 2: Follow with 2 pumps of Peptide Facial Refining Concentrate, massaging gently into the face and neck.
  • Step 3: Finish by layering additional targeted serums, such as Rozatrol, if desired.

If you’re unsure how to incorporate the Peptide Facial Refining Concentrate into your routine, we’re here to guide you. Our Skin Experts can walk you through the correct application method and show you step by step how to layer it with other products for the best results.

 

Book your free video skincare consultation now

 

How Long Will a Bottle Last?

ZO Skin Health Peptide Facial Refining Concentrate

A 30 ml bottle of the Peptide Facial Refining Concentrate typically provides around 59 applications, which works out to roughly 6 weeks when used twice daily on the face and neck. Individual usage may vary depending on how much product you apply each time.

 

How Much Does ZO Skin Health Peptide Facial Refining Concentrate Cost?


The ZO Skin Health Peptide Facial Refining Concentrate is priced at £220.00. This reflects the premium, science-backed formulation and the concentrated peptide technologies it contains, designed to deliver noticeable improvements in skin lift, firmness, and overall radiance. Investing in this serum means bringing professional-grade results into your daily routine, supporting healthier, more youthful-looking skin over time.

 

How Can I Buy ZO Skin Health Peptide Facial Refining Concentrate?

Close-up of a woman smiling with smooth, healthy skin

ZO Skin Health products are available exclusively through authorised clinic stockists, including Face Dr. To purchase, you’ll need a free online consultation with one of our Skin Experts, who will advise if the product is suitable for your skin.

After your consultation, you can buy the Peptide Facial Refining Concentrate directly through your Face Dr account.

 

Not Sure If This Product Is Right for You?


The Peptide Facial Refining Concentrate is a high-potency peptide serum designed to complement injectable treatments or act as a non-invasive option for clients seeking visible rejuvenation. Suppose you’re unsure whether it’s suitable for your skin or routine. In that case, our Skin Experts can provide personalised guidance through a free online consultation, helping you integrate it safely and effectively into your skincare plan.

 

Book your free video skincare consultation now

 

Summary: Should You Try ZO Skin Health Peptide Facial Refining Concentrate?


If you’re looking to support a smoother, lifted, and more youthful-looking complexion, ZO Skin Health Peptide Facial Refining Concentrate is a high-potency serum designed to complement injectable treatments or serve as a non-invasive option for visible rejuvenation. Its science-backed peptide technology makes it perfect for integrating professional-grade anti-ageing care into your daily routine.

Our Skin Experts at Face Dr are ready to provide personalised guidance, helping you determine if this serum is right for your skin and showing you how to use it effectively alongside other professional treatments. Curious to see how it could work for you? Book a free online consultation and receive tailored advice on incorporating the Peptide Facial Refining Concentrate into your routine.

 

Book your free video skincare consultation now

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